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An unscrupulous agent for the Borgias suffers a change of heart when asked to betray a noble count and his much younger, very beautiful wife. The neural sources of phasic DA signals may also be more complex than the simple feedforward pathways we have proposed, since the neural structures that communicate with DA neurons are densely interconnected Geisler and Zahm, and DA neurons can communicate with each other within the midbrain Ford et al. Emotion, motivation, and the brain: DA neurons are excited by sensory cues that are alerting left, black but do not respond when the same cues are rendered non-alerting right, gray. These neurons were recorded in anesthetized rats and were confirmed to be dopaminergic using juxtacellular labeling.

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Adapted from Guarraci and Kapp,

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Dopamine in motivational control: rewarding, aversive, and alerting

Ferris convinces his friend Cameron Frye, who is legitimately absent due to illness, to help lure Ferris' girlfriend Sloane Peterson out of school by reporting that her grandmother has died. Destinations of motivational salience signals According to our hypothesis, motivational salience coding DA neurons should project to brain regions involved in orienting, cognitive processing, and general motivation Figure 5. The Miseducation of Cameron Post The neurotransmitter dopamine DA has a crucial role in motivational control — in learning what things in the world are good and bad, and in choosing actions to gain the good things and avoid the bad things. Ferris flexes his hand in pain after supposedly catching the foul ball. The role of dopamine in conditioning and latent inhibition: Edit Details Official Sites:

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